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Cu-Chelated polydopamine nanoparticles as a photothermal medium and “immunogenic cell death” inducer for combined tumor therapy

Na XuCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. ChinaAo HuCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. ChinaXiming PuCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. ChinaJuan WangCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. ChinaXiaoming LiaoCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. ChinaZhongbing HuangCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. ChinaGuangfu YinCollege of Biomedical Engineering, Sichuan University, Chengdu 610065, P. R. China
2022en
ABI

Abstract

tumor vaccine-like functions, which were able to trigger a systemic antitumor immune response, preventing recurrence and metastasis without any other adjuvant supplementation. Overall, these Cu-PDA NPs will provide inspiration for the construction of a versatile nanoplatform for tumor therapy.

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