Antioxidant and hypoglycemic activities of exopolysaccharide by submerged culture of inocutus hispidus
Chunping XuCollege of Food and Biological Engineering, Zhengzhou University of Light Industry, Henan-450 002, ChinaShing‐Hwa LiuTechnical center of China Tobacco Guangxi Industrial Co. Ltd., Nanning-530 001, ChinaSW SunCollege of Food and Biological Engineering, Zhengzhou University of Light Industry, Henan-450 002, ChinaZF TianTechnical center of China Tobacco Guangxi Industrial Co. Ltd., Nanning-530 001, ChinaJY WuDepartment of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, ChinaXingliang LiTechnical center of China Tobacco Guangxi Industrial Co. Ltd., Nanning-530 001, China
2015en
ABI
Abstract
This work was to investigate the hypoglycemic and antioxidant activities of the exopolysaccharides produced in a stirred-tank bioreactor by Inocutus hispidus. The exopolysaccharides showed significant antioxidant activities, up to 70.7±2.5% inhibition of hydroxyl radicals, 50% inhibition of 2,2-diphenyl-1-picrylhydrazyl radicals, and a Trolox equivalent antioxidant capacity of 3.3 mM. The exopolysaccharide also showed notable hypoglycemic effects in streptozotocin-induced diabetic mice, reducing the plasma glucose, total cholesterol and triacylglycerol concentrations by 18.2±1.5, 20.9±0.8 and 14.4±0.4, respectively. The results demonstrated the potential of this EPS for human health protection against oxidative damage and hyperglycemia.
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