Caloporoside, a new inhibitor of phospholipases C from Caloporus dichrous (Fr.) Ryv.
Wolfgang WeberDepartment of Biotechnology, University of Kaiserslautern, GermanyPeter SchuDepartment of Biotechnology, University of KaiserslauternTimm AnkeDepartment of Biotechnology, University of KaiserslauternRobert VeltenWölfgang Steglich
1994en
ABI
Abstract
A new salicylic acid derivative, caloporoside, was isolated from fermentations of Caloporus dichrous. Its structure was elucidated by a combination of chemical and spectroscopic methods. Caloporoside exhibits weak antibacterial and antifungal activities and is a quite selective inhibitor of phospholipase C isolated from pig brain (Ki 12, 3 microM).
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