Glutathione-Coated Magnetic Nanoparticles for One-Pot Synthesis of 1,4-Dihydropyridine Derivatives
Behrooz MalekiDepartment of Chemistry, Hakim Sabzevari University, Sabzevar, IranHengameh AtharifarDepartment of Chemistry, Hakim Sabzevari University, Sabzevar, IranOliver ReiserInstitut für Organische Chemie, Universität Regensburg, Regensburg, GermanyReihaneh SabbaghzadehDepartment of Biology, Faculty of Science, Hakim Sabzevari University, Sabzevar, Iran
2019en
ABI
Abstract
A magnetic Fe3O4 supported glutathione catalyst was synthesized in a convenient and eco-friendly manner and characterized using FT-IR, XRD, TGA, TEM, VSM, EDX, and elemental analysis. This nano-organocatalyst exhibited excellent catalytic activity in the synthesis of a wide variety of 1,4-dihydropyridine derivatives. The catalyst was easily separated from the reaction mixture through using an external magnet and was reused in six consecutive runs with only a slight decrease in its catalytic activity. Other significant advantages of this method are shorter reaction time, excellent yield, simple work-up procedure, easy catalyst handling, and the high stability of the catalyst, which renders the protocol economic and sustainable.
Identifiers
Citations and references
Cited by 40 references