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Antimicrobial Activity of 4-Hydroxybenzoic Acid and<i>trans</i>4-Hydroxycinnamic Acid Isolated and Identified from Rice Hull

Jeong-Yong CHODepartment of Food Science and Technology, Chonnam National University, Kwangju, KoreaJae-Hak MOONPlant Biochemistry Research UnitKi-Young SeongDivision of Applied Plant Science, Chonnam National UniversityKeun-Hyung PARKDepartment of Food Science and Technology, Chonnam National University
1998en
ABI

Abstract

Two antimicrobial substances in rice hull were isolated and identified as 4-hydroxybenzoic acid and trans 4-hydroxycinnamic acid by LC-MS, and 1H- and 13C-NMR. An evaluation of 50% inhibition of growth (IC50) revealed that the two substances had different inhibition profiles against various microorganisms. Most of the gram-positive and some gram-negative bacteria were sensitive to trans 4-hydroxycinnamic acid and 4-hydroxybenzoic acid at IC50 concentrations of 100-170 and 160 micrograms/ml, respectively.

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