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Oxidized Mitochondrial DNA Activates the NLRP3 Inflammasome during Apoptosis

Kenichi ShimadaDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USATimothy R. CrotherDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USAJustin N. KarlinDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USAJargalsaikhan DagvadorjDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USANorika ChibaDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USAShuang ChenDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USAV. Krishnan RamanujanDepartment of Surgery, Cedars Sinai Medical Center, Los Angeles, CA 90048, USAAndrea J. WolfImmunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USALaurent VergnesDepartment of Human Genetics, UCLA, Los Angeles, CA 90095, USADavid M. OjciusHealth Sciences Research Institute and School of Natural Sciences, UC Merced, Merced, CA 95343, USAAltan RentsendorjRegenerative Medicine Institute, Departments of Biomedical Sciences and Neurosurgery, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USAMario H. VargasDepartment of Chemistry, UC Riverside, Riverside, CA 92521, USACandace GuerreroDepartment of Chemistry, UC Riverside, Riverside, CA 92521, USAYinsheng WangDepartment of Chemistry, UC Riverside, Riverside, CA 92521, USAKatherine A. FitzgeraldDivision of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USADavid M. UnderhillImmunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USATerrence TownRegenerative Medicine Institute, Departments of Biomedical Sciences and Neurosurgery, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USAMoshe ArditiDivision of Pediatrics Infectious Disease and Immunology, Cedars-Sinai Medical Center (CSMC) and David Geffen School of Medicine, UCLA, Los Angeles, CA 90048, USA
2012en
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