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Indices of multilocus linkage disequilibrium

Paul‐Michael AgapowDepartment of Biology, Imperial College, Silwood Park, Ascot, Berkshire, SL5 7PY, UKAustin BurtDepartment of Biology, Imperial College, Silwood Park, Ascot, Berkshire, SL5 7PY, UK
2001en
ABI

Abstract

Abstract Linkage disequilibrium is an ubiquitous biological phenomenon. However a common metric for disequilibrium – the index of association or I A – is dependent on sample size. In this paper we present a modification of I A that removes this dependency. This method has been implemented in a software package.

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Cited by 20 references