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New Lanostane-Type Triterpenes from Fomes officinalis

Xia WuInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical CollegeJun‐Shan YangInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical CollegeLiang ZhouInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical CollegeYuesheng DongInstitute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College
2004en
ABI

Abstract

Five new lanostane-type triterpenes, named fomefficinic acid A-E (1-5), were isolated from the dried sclerotium of Fomes officinalis, respectively. Their structures were established as 24-methylene-3-oxo-lanost-8-en-21-oic acid (1), 3alpha,15alpha-dihydroxy-24-methylene-lanosta-7,9(11)-dien-21-oic acid (2), 3alpha,15alpha-dihydroxy-24-methylene-lanost-8-en-21-oic acid (3), 15alpha-hydroxy-3-oxo-24-methylenelanost-8-en-21-oic acid (4), 15alpha-acetoxy-3-oxo-24-methylenelanosta-7,9(11)-dien-21-oic acid (5), by spectral analysis and chemical methods as well as comparison with known compounds.

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