Sustainable electrocatalytic oxidation of <i>N</i>-alkylamides to acyclic imides using H<sub>2</sub>O
Qi JingDepartment of Chemistry, National University of Singapore, 117545, SingaporeXiyan WangDepartment of Chemistry, National University of Singapore, 117545, SingaporeGan WangDepartment of Chemistry, National University of Singapore, 117545, SingaporeSrinivas Reddy DubbakaPfizer Manufacturing Pte Ltd, Manufacturing Technology Development Centre (MTDC), 138623, SingaporePatrick O’NeillPfizer Ireland Pharmaceuticals, Process Development Centre, Ringaskiddy (PDC), Co-Cork, 637578, IrelandHwee Ting AngDepartment of Chemistry, National University of Singapore, 117545, SingaporeJie WuDepartment of Chemistry, National University of Singapore, 117545, Singapore
2023en
ABI
Abstract
Green and environmentally friendly synthesis of imides from N -alkylamides via electrocatalytic oxidation with H 2 O as the oxygen source, yielding versatile imide building blocks for biologically relevant 1,2,4-triazole compounds.
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