Antiviral Activity of Some Plants Used in Nepalese Traditional Medicine
Meena RajbhandariResearch Center for Applied Science and Technology, Tribhuvan University, Kathmandu, NepalR MentelFriedrich-Loeffler-Institute of Medical Microbiology, Ernst-Moritz-Arndt-University Greifswald, Martin-Luther-Strasse 6, 17487 GreifswaldPramod Kumar JhaCentral Department of Botany, Tribhuvan University, KathmanduRam Prasad ChaudharyCentral Department of Botany, Tribhuvan University, KathmanduSumit BhattaraiCentral Department of Botany, Tribhuvan University, KathmanduMohan B. GewaliResearch Center for Applied Science and Technology, Tribhuvan University, KathmanduNeena KarmacharyaResearch Center for Applied Science and Technology, Tribhuvan University, KathmanduM. HipperInstitute of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17487 GreifswaldUlrike LindequistInstitute of Pharmacy, Ernst-Moritz-Arndt-University Greifswald, Friedrich-Ludwig-Jahn-Strasse 17, 17487 Greifswald
2007en
ABI
Abstract
Methanolic extracts of 41 plant species belonging to 27 families used in the traditional medicine in Nepal have been investigated for in vitro antiviral activity against Herpes simplex virus type 1 (HSV-1) and influenza virus A by dye uptake assay in the systems HSV-1/Vero cells and influenza virus A/MDCK cells. The extracts of Astilbe rivularis, Bergenia ciliata, Cassiope fastigiata and Thymus linearis showed potent anti-herpes viral activity. The extracts of Allium oreoprasum, Androsace strigilosa, Asparagus filicinus, Astilbe rivularis, Bergenia ciliata and Verbascum thapsus exhibited strong anti-influenza viral activity. Only the extracts of A. rivularis and B. ciliata demonstrated remarkable activity against both viruses.
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