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Plaque Formation in Agar by Single Antibody-Producing Cells

N. K. JerneDepartment of Microbiology, University of Pittsburgh Medical School, Pittsburgh 13, PennsylvaniaAlbert A. NordinDepartment of Microbiology, University of Pittsburgh Medical School, Pittsburgh 13, Pennsylvania
1963en
ABI

Abstract

Distinct plaques, each of which is due to the release of hemolysin by a single antibody-forming cell, are revealed by complement after incubation, in an agar layer, of a mixture of sheep red cells and lymphoid cells from a rabbit immunized with sheep red cells.

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Cited by 30 references