Saponins with Molluscicidal Properties from <i>Lonicera nigra</i><scp>L</scp>
Bruno DomonInstitut de pharmacognosie et phytochimie, Ecole de Pharmacie, Université de Lausanne, 2, rue Vuillermet, CH-1005 LausanneKurt HostettmannInstitut de pharmacognosie et phytochimie, Ecole de Pharmacie, Université de Lausanne, 2, rue Vuillermet, CH-1005 Lausanne
1983en
ABI
Abstract
Abstract Eight triterpenoid saponins (1–8) have been isolated from the berries of Lonicera nigra L . (Caprifoliaceae) by combination of droplet counter‐current chromatography and column chromatography on silica. The structures have been established by 1 H‐NMR., 13 C‐NMR. spectroscopy, FD.‐MS., FAB.‐MS. and D./CI.‐MS., and on the basis of acidic and basic hydrolyses. The monodesmosidic saponins 1–5 possess strong molluscicidal activity against the schistosomiasis‐transmitting snail Biomphalaria glabrata , whereas the bidesmosidic saponins 6–8 are inactive.
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