Article

Adsorption Capacity and Selectivity of Molecularly Imprinted Polymers towards β-Sitosterol

St. FauziahDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, IndonesiaNunuk Hariani SoekamtoDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, IndonesiaPrastawa BudiDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, IndonesiaPaulina TabaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Hasanuddin University, Jl. Perintis Kemerdekaan, KM 10, Makassar, Indonesia

2019en

ABI

Abstract

Molecularly imprinted polymers (MIP) as an adsorbent has been synthesized using β-sitosterol as molecule template on free radical polymerization reaction. The capacity and selectivity of the adsorption from MIP to β-sitosterol was studied in this study. The β-sitosterol concentration in the adsorption-desorption test and the MIP selectivity test were analyzed by UV-visible and HPLC. The MIP obtained from the synthesis results in a high adsorption capacity. Based on the Freundlich adsorption isothermal equation, the adsorption capacity (k) was found to be 1.24 mg/g. The MIP can adsorb 100 % β-sitosterol while cholesterol was only 3 %. The MIP is most selective to β-sitosterol, therefore, has high potential to apply as adsorbent at solid phase extraction method to isolate β-sitosterol from sample extract.

Identifiers

DOI: 10.14233/ajchem.2019.22141

Citations and references

Cited by 20 references

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