DETERMINING THE ROLE OF MMP-9 AND TIMP-1 POLYMORPHIC GENES IN SARS COV-2 INDUCED MYOCARDITIS.
Akhmedova Gulchehra AbdullaevnaAssistant, PhD Department of Internal Medicine No.1 named Associate Professor N. A.Abdullayev,Aminov Feruz RavshanbekovichSamarkand State Medical University. Student of group 604, Faculty of Medical PedagogyRasulov Rakhmatillo SaydullayevichSamarkand State Medical University. Maxillofacial surgeon at the Samarkand branch of the Republican Scientific and Practical Center of Traumatology and Orthopedics
Zenodo (CERN European Organization for Nuclear Research)repository2026
ABI
Abstract
Current evidence suggests that MMP and TIMP gene polymorphisms may have a significant impact on the degree of inflammation and structural changes in the myocardium during viral infections, including COVID-19. However, the results of studies remain contradictory due to differences in study groups, methodologies, and evaluation criteria. In addition, most of the studies have focused on general aspects of inflammation in myocarditis, and the exact mechanisms associated with genetic variants in the MMP and TIMP genes are poorly understood.
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