THE IMPACT OF STRESS ON THE FEMALE REPRODUCTIVE SYSTEM
Xodjayeva Dilnoza Bobirovna, Assistant of Kokand University Andijan branch
Zenodo (CERN European Organization for Nuclear Research)repository2026
ABI
Abstract
Chronic psychological stress represents a significant threat to female reproductive health through disruption of the hypothalamic-pituitary-ovarian axis and alteration of neuroendocrine signaling pathways. This investigation examines the mechanisms by which stress-induced cortisol elevation interferes with gonadotropin-releasing hormone pulsatility, leading to anovulation, menstrual irregularities, and impaired fertility outcomes. Analysis of clinical and experimental data demonstrates that sustained activation of the hypothalamic-pituitary-adrenal axis creates hormonal imbalances that compromise ovarian function and reduce conception probability by approximately 30 percent in women experiencing chronic stress.
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