DETERMINING THE ROLE OF MMP-9 AND TIMP-1 POLYMORPHIC GENES IN THE BLOOD OF PATIENTS WITH MYOCARDITIS COMPLICATED BY SARS-COV-2.
Akhmedova Gulchehra AbdullaevnaActing Associate Professor of the Department of Internal Medicine No. 1 of the Samarkand State Medical UniversitySharipov Tokhirjon Rabbimkul ugliActing Associate Professor of the Department of Internal Medicine No. 1 of the Samarkand State Medical UniversityAbdullayeva Madina Olimjon qiziPhD. Resident physician of the Republican Scientific and Practical Medical Center for Specialized Therapy and Medical Rehabilitation
Open MINDrepository2026
ABI
Abstract
Current evidence suggests that MMP and TIMP gene polymorphisms may have a significant impact on the degree of inflammation and structural changes in the myocardium during viral infections, including COVID-19. However, the results of studies remain contradictory due to differences in study groups, methodologies, and evaluation criteria. In addition, most of the studies have focused on general aspects of inflammation in myocarditis, and the exact mechanisms associated with genetic variants in the MMP and TIMP genes are poorly understood.
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