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ETIOPATHOGENESIS OF FEBRILE SEIZURES

Djamilova Jamila SattorovnaDepartment of Preclinical Sciences of the Asia International University. Bukhara, Uzbekistan
ABI

Abstract

Febrile seizures (FS) are the most common seizure disorder in young children. They typically happen between 6 months and 5 years of age when a child has a fever — but no brain infection, metabolic problem, or history of seizures without fever. The causes are complex and involve several things working together: a child’s genes, how their brain is still developing, and the body’s natural inflammatory response to infection. Recent research has spotlighted one key player — a chemical called interleukin-1β (IL-1β) — that ramps up brain cell activity and makes seizures more likely. This article explains the main triggers and mechanisms in plain language.

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