"MAIN PANCREATIC DUCT STENOSIS AS A COMPLICATION OF CHRONIC PANCREATITIS."
Abstract
Chronic pancreatitis is a progressive inflammatory disease of the pancreas characterized by irreversible morphological changes and gradual impairment of both exocrine and endocrine functions. One of the significant complications of chronic pancreatitis is stenosis of the main pancreatic duct, which leads to impaired outflow of pancreatic secretions, increased intraductal pressure, and progression of pancreatic tissue damage. The development of pancreatic duct stenosis is associated with chronic inflammation, fibrosis, and structural remodeling of the pancreatic parenchyma. Clinically, this condition may manifest with persistent abdominal pain, recurrent exacerbations of pancreatitis, and digestive disorders. Timely diagnosis plays a crucial role in preventing further complications. Modern diagnostic methods include ultrasound examination, computed tomography (CT), magnetic resonance cholangiopancreatography (MRCP), and endoscopic retrograde cholangiopancreatography (ERCP). Management of main pancreatic duct stenosis depends on the severity of the condition and may include conservative therapy, endoscopic interventions, or surgical treatment aimed at restoring ductal patency and relieving symptoms. Early detection and appropriate therapeutic strategies contribute to improved patient outcomes and prevention of disease progression.