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ACUTE RESPIRATORY DISTRESS SYNDROME IN BURN PATIENTS

Najmiddinov Z.ASamarkand State Medical UniversityRuziboev S.ASamarkand State Medical University
ABI

Abstract

Acute Respiratory Distress Syndrome (ARDS) represents a severe pulmonary complication that may develop following burn injury. Its pathogenesis involves either direct damage to lung tissue caused by inhalation of smoke and toxic gases or an indirect systemic inflammatory response triggered by burn trauma and subsequent infections. This prospective cohort study was conducted between January and December 2025 to evaluate the incidence, severity, and determinants of ARDS among burn patients. Clinical, demographic, and prognostic data, including burn extent and depth, were systematically collected. A total of 85 patients were included. The mean total body surface area (TBSA) affected was 28.3%, and inhalation injury was identified in 35.3% of cases. ARDS developed in 38.6% of patients requiring invasive mechanical ventilation. Mortality remained high and demonstrated a strong association with ARDS occurrence.

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