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Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment

Qianghu WangDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USABaoli HuDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAXin HuDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; University of Texas-Houston Graduate School in Biomedical Sciences, Houston, TX 77030, USAHoon KimDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USAMassimo SquatritoCancer Cell Biology Programme, Seve Ballesteros Foundation Brain Tumor Group, Centro Nacional de Investigaciones Oncológicas, CNIO, 28029 Madrid, SpainLisa ScarpaceDepartments of Neurology and Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USAAna C. deCarvalhoDepartments of Neurology and Neurosurgery, Henry Ford Hospital, Detroit, MI 48202, USASali LyuKey Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China; Collaborative Innovation Center for Cardiovascular Disease, Nanjing Medical University, Nanjing 211166, ChinaPengping LiKey Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China; Collaborative Innovation Center for Cardiovascular Disease, Nanjing Medical University, Nanjing 211166, ChinaYan LiKey Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China; Collaborative Innovation Center for Cardiovascular Disease, Nanjing Medical University, Nanjing 211166, ChinaFloris P BarthelDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USAHee Jin ChoInstitute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, KoreaYu-Hsi LinDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USANikunj SataniDepartment of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAEmmanuel Martínez-LedesmaDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USASiyuan ZhengDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAEdward F. ChangDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USACharles-Etienne Gabriel SauvéDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAAdriana OlarDepartments of Pathology and Laboratory Medicine, Neurosurgery Medical University of South Carolina, and Hollings Cancer Center, Charleston, SC 29425, USAZheng D. LanDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAGaetano FinocchiaroUnit of Molecular Neuro-Oncology, Fondazione IRCCS Istituto Neurologico C. Besta, 20133 Milano, ItalyJoanna J. PhillipsDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USAMitchel S. BergerDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USAKonrad GabrusiewiczDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAGuocan WangDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAEskil EskilssonDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAJian HuDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USATom MikkelsenKey Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, ChinaRonald A. DePinhoDepartment of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAFlorian L. MüllerDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAAmy B. HeimbergerDepartment of Neurosurgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAErik P. SulmanDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: [email protected]Do‐Hyun NamInstitute for Refractory Cancer Research, Samsung Medical Center, Seoul 06351, Korea; Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Seoul 06351, Korea; Department of Neurosurgery Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 06351, Korea. Electronic address: [email protected]Roel G.W. VerhaakDepartment of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Electronic address: [email protected]
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