Brain scintigrams in metastatic carcinoma

A review of clinical experience with two agents used in brain tumor imaging, 203Hg-chlormerodrin and 99mTc-pertechnetate, was made to determine true-positive and false-positive rates for the localization of metastatic brain tumors. We found no significant difference between the two agents in the true-positive rate, 70% and 65%, respectively. False-positive rate also revealed no significant differences, 12% and 5%, respectively. Experience with delayed scans using 99mTc-pertechnetate suggests that true-positive rates may be increased with a longer interval between injection and scan than was employed in most of these patients. Newer radiopharmaceuticals currently under investigation may also offer improved tumor detection.

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