InterPregGen:genetic studies of pre-eclampsia in three continents
Linda MorganSchool of Life Sciences, University of Nottingham, UKRalph McGinnisWellcome Trust Sanger Institute, UKValgerður SteinthórsdóttirdeCODE Genetics, IcelandGulnara SvyatovaNodira ZakhidovaInstitute of Immunology, Uzbek Academy of Science, UzbekistanWai LeeBHF Glasgow Cardiovascular Research Centre, University of Glasgow, UKAnn‐Charlotte IversenDepartment of Cancer Research and Molecular Medicine and Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, NorwayPer MagnusNorwegian Institute of Public Health, NorwayJames J. WalkerLeeds Institute of Biomedical and Clinical Sciences, University of Leeds, UKJuan P. CasasLondon School of Hygiene and Tropical Medicine and University College London, UKSaidazim SultanovRepublic Specialized Scientific-Practical Medical Centre of Obstetrics and Gynaecology, UzbekistanHannele LaivuoriHaartman Institute, Medical Genetics, University of Helsinki, Finland
ABI
Аннотация
Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of genetic variants which predispose to pre-eclampsia demands large DNA collections from affected mothers and babies and controls, with reliable supporting phenotypic data. The InterPregGen study has assembled a consortium of researchers from Europe, Central Asia and South America with the aim of elucidating the genetic architecture of pre-eclampsia. The MoBa collection is playing a vital role in this collaborative venture, which has the potential to provide new insights into the causes of pre-eclampsia, and provide a rational basis for novel approaches to prevention and treatment.
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