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Possibilities of using Cytoflavin in the treatment of cognitive and emotional disorders in patients with tension headaches

Л С ЧуткоN. Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, RussiaS Yu SurushkinaN. Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, RussiaE A YakovenkoN. Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, RussiaА В РожковаN. Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, RussiaM B VolovN. Bekhtereva Institute of Human Brain Russian Academy of Sciences, St. Petersburg, RussiaNadezda ZhukovskayaLeningrad Regional Clinical Hospital, St. Petersburg, RussiaE.N. MajidovaTashkent Pediatric Medical Institute, Tashkent, Uzbekistan
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OBJECTIVE: To evaluate the efficacy and safety of Сytoflavin in the treatment of cognitive and emotional disorders in patients with tension headache. MATERIAL AND METHODS: Fifty patients with tension headache, aged from 18 to 50 years, were studied. The following methods and tests were used: neurological examination, NPRS, STAI, CFQ, RAVLT, TOVA, electroencephalography (routine and spectral analysis). The patients were treated with Сytoflavin. RESULTS: After the treatment, clinical improvement was observed in 62.0% of the patients. A significant decrease in trait anxiety and inattention, as well as an improvement of memory performance were observed. A comparative analysis of neurophysiological results before and after the treatment showed a decrease in the manifestations of dysfunction of nonspecific regulation of the brain. CONCLUSION: The results of this study demonstrate the efficacy of Cytoflavin in the treatment of tension headache and associated emotional and cognitive impairments.

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