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The Role of Xenobiotic Enzyme Genes of the First and Second Phases in the Pathogenesis of Fetal Growth Restriction Syndrome

Mavlyanova NNRepublican Specialized Scientific and Practical Medical Center of Obstetrics and Gynecology Under the Ministry of Health of the Republic of Uzbekistan, Uzbekistan
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The article presents the results of molecular genetic studies of genes of biotransformation enzymes of xenobiotics of the first and second phase in pregnant women with fetal growth restriction syndrome. Using the del/del genotype variants of the GSTM1 and GSTT1 genes and G alleles of the GSTP1 gene, one can determine the prognosis of the risk of developing fetal loss syndrome, characterized by impaired detoxification during pregnancy.

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