Synthesis Of 2,5-Dimersapto-1,3,4-Thiadiazol Products
Jololiddinov Fazliddin Yuldashali UgliXaitboev XamidBoboev Baxrom NurillaevichDoctor Of Chemical Sciences, Professor, Head Of The Department Of Chemistry Of Natural Compounds, Faculty Of Chemistry, National University Of Uzbekistan
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Аннотация
Potentially bioactive 2,5-bis derivatives of 1,3,4-thiadiazole with alkaloid moieties were synthesized byreaction of 1,3,4-thiadiazol-2,5-dithiol with N-acryloyl-substituted derivatives of the alkaloids anabasine,cytisine, and D-pseudoephedrine.1,3,4-Thiadiazole-2,5-disulfonic acid was synthesized by oxidation of 2,5-dimercapto-1,3,4-thiadiazole,and onium salts of this acid were prepared by its reactions with selected alkaloids and secondaryamines.
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