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Sensitization to Salsola kali pollen depends on the age of the patients

Nigora MagbulovaStefania KatsamakiElnara IsmailovaMokhigul IsmatovaGulnara DjambekovaYuliya LevitskayaVictoriya GaribMinistry of Innovative Development of the Republic of Uzbekistan, tashkent, Uzbekistan
2020en
ABI

Аннотация

The aim of the study was to study the characteristics of The IgE profile of sensitization to weeds, and in particular to Salsola kali, depending on the age of patients with respiratory allergies who live in the city of Tashkent. The serum of 401 patients with confirmed respiratory Allergy symptoms was tested using the Alex research allergo test (Macro Array Diagnostics). statistical analysis of the data was performed using IBM SPSS 20 and Microsoft Excel. Analysis of sensitization profiles showed that among 401 patients, specific IgE to Salsola kali were detected in 154 people, which is 38%, which indicates that this allergenic source is predominant in sensitization to weeds presented in the research chip. Most often, sensitization to Salsola kali was determined in patients aged 4 to 18 years - only 98 cases (almost 64% among all those sensitive to Salsola kali), while the largest number of sensitized to this source of Allergy was in the group "children" aged 4-11 years – 53 cases-almost 34.5% of all detected cases of sensitivity to Salsola kali. In the groups of patients aged 19-29 and 30-45 years, there were fewer cases – 28 patients (on average, this is 18% for each age group). There were no statistically significant gender differences in sensitivity to Salsola kali. The data obtained confirm the need for mandatory inclusion in the chip diagnostics of the major allergen Sal k1 in this region and for preventive and preventive measures in relation to allergosensitization to Salsola kali, especially in patients under the age of 18 years

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