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Clinical manifestations of bronchial asthma and chronic obstructive pulmonary disease in adults

Ya N. FayzullaevaInstitute of Immunology and Human Genomics, Academy of Sciences of the Republic of UzbekistanA. A. RaufovInstitute of Immunology and Human Genomics, Academy of Sciences of the Republic of Uzbekistan
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AbstractBackground: Bronchial asthma (BA) and chronic obstructive bronchitis (COPD) are one of the most common respiratory diseases in children and adults all over the world, leading to socioeconomic and medical losses to society. The problem of BA and COPD has been insufficiently studied; information on the dependence of manifestations on the age at which BA and COPD debuted is absent in the literature. The aim of the study was to study the features of the clinical manifestations of BA and COPD, as well as to determine the prognosis of the disease in adult patients and, on the basis of the data obtained, to develop measures to improve the clinical assessment of the condition and treatment tactics. Objects and methods of research: In 25 patients with bronchial asthma (group 1), the circumstances of the onset of the disease, its manifestations and the results of treatment were compared with those of 25 patients with COPD (group 2). The prescription and circumstances of the onset of BA, the nature of concomitant pathology, and the relationship with heredity were revealed. In the groups, the following were assessed: general blood analysis, general urine analysis, biochemical blood test, general sputum analysis, FVD, shadow picture in the lungs, ECG, EEG, ultrasound and the functional state of the thyroid gland (TTG, T3, T4), immune status. Results and conclusions: it was proved that the circumstances of the onset, manifestations of the disease and the effectiveness of treatment are different depending on the age at which BA and COPD first appeared.

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