IMMUNOLOGICAL STATUS IN SICK CHILDREN WITH CONGENITAL CLEFT UPPER LIP AND PALATE

The aim of the study was to study the level of pro - and anti-inflammatory cytokines in sickchildren with congenital cleft upper lip and palate. The material on the registration of malformationsin the Bukhara region for 2018-2020 was studied. Of the 110 infants born with various intrauterineabnormalities – 15% () revealed cleft upper lip and palate. 20 practically healthy children made up thecontrol group. The study of the level of IL-2, IL-4, IL-6, IL-18 and MSP-1 was carried out in the bloodserum by IFA.

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