Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019
Jonathan KocarnikInstitute for Health Metrics and Evaluation, University of Washington, SeattleKelly ComptonInstitute for Health Metrics and Evaluation, University of Washington, SeattleFrances DeanInstitute for Health Metrics and Evaluation, University of Washington, SeattleWeijia FuInstitute for Health Metrics and Evaluation, University of Washington, SeattleBrian GawInstitute for Health Metrics and Evaluation, University of Washington, SeattleJames HarveyInstitute for Health Metrics and Evaluation, University of Washington, SeattleHannah HenriksonDepartment of Global Health, Boston University, Boston, MassachusettsDan LuInstitute for Health Metrics and Evaluation, University of Washington, SeattleAlyssa PenniniInstitute for Health Metrics and Evaluation, University of Washington, SeattleRixing XuInstitute for Health Metrics and Evaluation, University of Washington, SeattleEmad AbabnehPathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OhioMohsen Abbasi‐KangevariSocial Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IranHedayat AbbastabarAdvanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Sciences, Tehran, IranSherief Abd‐ElsalamTropical Medicine Department, Tanta University, Tanta, EgyptAmir AbdoliZoonoses Research Center, Jahrom University of Medical Sciences, Jahrom, IranAidin AbediDepartment of Orthopaedic Surgery, University of Southern California, Los AngelesHassan AbidiLaboratory Technology Sciences Department, Yasouj University, Yasuj, IranHassan AbolhassaniDepartment of Laboratory Medicine, Karolinska University Hospital, Huddinge, SwedenIsaac Akinkunmi AdedejiDepartment of Sociology, Olabisi Onabanjo University, Ago-Iwoye, NigeriaQorinah Estiningtyas Sakilah AdnaniDepartment of Midwifery, Auckland University of Technology, Auckland, New ZealandShailesh M AdvaniSchool of Medicine, Georgetown University, Washington, DCMuhammad U. AfzalDepartment of Life Sciences, University of Management and Technology, Lahore, PakistanMohammad AghaaliDepartment of Epidemiology and Biostatistics, Qom University of Medical Sciences, Qom, IranBright Opoku AhinkorahThe Australian Centre for Public and Population Health Research, University of Technology Sydney, Sydney, New South Wales, AustraliaSajjad AhmadFoundation University Medical College, Foundation University Islamabad, Islamabad, PakistanTauseef AhmadDepartment of Epidemiology and Health Statistics, Southeast University, Nanjing, ChinaAli AhmadiDepartment of Epidemiology and Biostatistics, Shahrekord University of Medical Sciences, Shahrekord, IranSepideh AhmadiSchool of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IranTarik A. RashidDepartment of Computer Science and Engineering, University of Kurdistan Hewler, Erbil, IraqYusra Ahmed SalihCollege of Informatics, Sulaimani Polytechnic University, Sulaymaniyah, IraqGizachew Taddesse AkaluMicrobial, Cellular and Molecular Biology, Addis Ababa University, Addis Ababa, EthiopiaAddis AkliluDepartment of Medical Laboratory Sciences, Arba Minch University, Arba Minch, EthiopiaTayyaba AkramSchool of Mathematical Sciences, University of Science Malaysia, Penang, MalaysiaChisom Joyqueenet AkunnaDepartment of Public Health, Federal Ministry of Health, Garki, NigeriaHanadi Al HamadGeriatric and Long-Term Care Department, Hamad Medical Corporation, Doha, QatarFares AlahdabMayo Evidence-Based Practice Center, Mayo Clinic Foundation for Medical Education and Research, Rochester, MinnesotaZiyad Al‐AlyClinical Epidemiology Center, Department of Veterans Affairs, St Louis, MissouriSaqib AliDepartment of Information Systems, Sultan Qaboos University, Muscat, OmanYousef AlimohamadiDepartment of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, IranVahid AlipourDepartment of Health Economics, Iran University of Medical Sciences, Tehran, IranSyed Mohamed AljunidDepartment of Health Policy and Management, Kuwait University, Safat, KuwaitMotasem AlkhayyatDepartment of Internal Medicine, Cleveland Clinic, Cleveland, OhioAmir Almasi‐HashianiDepartment of Epidemiology, Arak University of Medical Sciences, Arak, IranNihad A. AlmasriPhysiotherapy Department, University of Jordan, Amman, JordanSadeq Ali Al‐MaweriCollege of Dental Medicine, Qatar University, Doha, QatarSami AlmustanyirCollege of Medicine, Alfaisal University, Riyadh, Saudi ArabiaNivaldo AlonsoDepartment of Surgery, University of São Paulo, São Paulo, BrazilNelson Alvis‐GuzmánResearch Group in Health Economics, University of Cartagena, Cartagena, ColombiaHubert AmuDepartment of Population and Behavioural Sciences, University of Health and Allied Sciences, Ho, GhanaEtsay Woldu AnbesuDepartment of Public Health, Samara University, Samara, EthiopiaRobert AncuceanuPharmacy Department, Carol Davila University of Medicine and Pharmacy, Bucharest, RomaniaFereshteh AnsariRazi Vaccine and Serum Research Institute, Agricultural Research, Education, and Extension Organization, Tehran, IranAlireza Ansari‐MoghaddamDepartment of Epidemiology and Biostatistics, Zahedan University of Medical Sciences, Zahedan, IranMaxwell Hubert AntwiClinical Laboratory Department, Ghana Health Service, Kumasi, GhanaDavood AnvariDepartment of Parasitology, Iranshahr University of Medical Sciences, Iranshahr, IranAnayochukwu Edward AnyasodorSchool of Community Health, Charles Sturt University, Orange, New South Wales, AustraliaMuhammad AqeelDepartment of Psychology, Foundation University Islamabad, Rawalpandi, PakistanJalal ArablooHealth Management and Economics Research Center, Iran University of Medical Sciences, Tehran, IranMorteza Arab‐ZozaniSocial Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, IranOlatunde AremuDepartment of Public Health, Birmingham City University, Birmingham, EnglandHany AriffinDepartment of Paediatrics, University of Malaya, Kuala Lumpur, MalaysiaTimur AripovBoston Children's Hospital, Boston, MassachusettsMuhammad ArshadAllied Health Sciences, Khyber Medical University, Timergara, Lower Dir, PakistanAl ArtamanZayed University, Abu Dhabi, United Arab EmiratesJudie ArulappanDepartment of Maternal and Child Health, Sultan Qaboos University, Muscat, OmanZatollah AsemiResearch Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, IranMohammad Asghari JafarabadiDepartment of Biostatistics and Epidemiology, Tabriz University of Medical Sciences, Tabriz, IranTahira AshrafInstitute of Radiological Sciences and Medical Imaging Technology, University of Lahore, Lahore, PakistanPrince AtorkeyHunter New England Population Health, Wallsend, New South Wales, AustraliaAvinash AujayebNorthumbria HealthCare National Health Service (NHS) Foundation Trust, NHS England, Newcastle upon Tyne, EnglandMarcel AusloosDepartment of Statistics and Econometrics, Bucharest University of Economic Studies, Bucharest, RomaniaAtalel Fentahun AwedewDepartment of Surgery, Addis Ababa University, Addis Ababa, EthiopiaBeatriz Paulina Ayala QuintanillaSan Martin de Porres University, Lima, PeruTemesgen AyenewDepartment of Nursing, Debre Markos University, Debre Markos, EthiopiaMohammed A. AzabDepartment of Neurosurgery, Cairo University, Cairo, EgyptSina AzadnajafabadNoncommunicable Diseases Research Center, Tehran, IranAmirhossein Azari JafariSchool of Medicine, Shahroud University of Medical Sciences, Shahroud, IranGhasem AzarianDepartment of Environmental Health Engineering, Hamadan University of Medical Sciences, Hamadan, IranAhmed Y. AzzamFaculty of Medicine, October 6 University, 6th of October City, EgyptAshish BadiyeDepartment of Forensic Science, Government Institute of Forensic Science, Nagpur, IndiaSaeed BahadoryDepartment of Parasitology, Alborz University of Medical Sciences, Karaj, IranAtif Amin BaigUnit of Biochemistry, Universiti Sultan Zainal Abidin, Kuala Terengganu, MalaysiaJennifer L. BakerCenter for Clinical Research and Prevention, Bispebjerg University Hospital, Frederiksberg, DenmarkSenthilkumar BalakrishnanDepartment of Medical Microbiology, Haramaya University, Harar, EthiopiaMaciej BanachDepartment of Hypertension, Medical University of Lodz, Lodz, PolandTill BärnighausenHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, GermanyFrancesco Barone‐AdesiDepartment of Translational Medicine, University of Eastern Piedmont, Novara, ItalyFabio BarraAcademic Unit of Obstetrics and Gynecology, University of Genoa, Genoa, ItalyAmadou BarrowDepartment of Public and Environmental Health, University of the Gambia, Brikama, The GambiaMasoud BehzadifarSocial Determinants of Health Research Center, Lorestan University of Medical Sciences, Khorramabad, IranUzma BelgaumiDepartment of Oral Pathology and Microbiology, Krishna Institute of Medical Sciences, Karad, IndiaWoldesellassie BezabheBahir Dar University, Bahir Dar, EthiopiaYihienew Mequanint BezabihDepartment of Internal Medicine, Bahir Dar University, Bahir Dar, EthiopiaDevidas S. BhagatDepartment of Forensic Chemistry, Government Institute of Forensic Science, Aurangabad, IndiaAkshaya Srikanth BhagavathulaDepartment of Social and Clinical Pharmacy, Charles University, Hradec Kralova, Czech RepublicNikha BhardwajDepartment of Anatomy, Government Medical College Pali, Pali, IndiaPankaj BhardwajDepartment of Community Medicine and Family Medicine, All India Institute of Medical Sciences, Jodhpur, IndiaSonu BhaskarDepartment of Neurology and Neurophysiology, South West Sydney Local Heath District and Liverpool Hospital, Sydney, New South Wales, AustraliaKrittika BhattacharyyaDepartment of Statistical and Computational Genomics, National Institute of Biomedical Genomics, Kalyani, IndiaVijayalakshmi S BhojarajaDepartment of Anatomy, Manipal University College Melaka, Melaka, Malaysia
ABI
Аннотация
IMPORTANCE: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. OBJECTIVE: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. EVIDENCE REVIEW: The GBD 2019 estimation methods were used to describe cancer incidence, mortality, years lived with disability, years of life lost, and disability-adjusted life years (DALYs) in 2019 and over the past decade. Estimates are also provided by quintiles of the SDI, a composite measure of educational attainment, income per capita, and total fertility rate for those younger than 25 years. Estimates include 95% uncertainty intervals (UIs). FINDINGS: In 2019, there were an estimated 23.6 million (95% UI, 22.2-24.9 million) new cancer cases (17.2 million when excluding nonmelanoma skin cancer) and 10.0 million (95% UI, 9.36-10.6 million) cancer deaths globally, with an estimated 250 million (235-264 million) DALYs due to cancer. Since 2010, these represented a 26.3% (95% UI, 20.3%-32.3%) increase in new cases, a 20.9% (95% UI, 14.2%-27.6%) increase in deaths, and a 16.0% (95% UI, 9.3%-22.8%) increase in DALYs. Among 22 groups of diseases and injuries in the GBD 2019 study, cancer was second only to cardiovascular diseases for the number of deaths, years of life lost, and DALYs globally in 2019. Cancer burden differed across SDI quintiles. The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. While the high SDI quintile had the highest number of new cases in 2019, the middle SDI quintile had the highest number of cancer deaths and DALYs. From 2010 to 2019, the largest percentage increase in the numbers of cases and deaths occurred in the low and low-middle SDI quintiles. CONCLUSIONS AND RELEVANCE: The results of this systematic analysis suggest that the global burden of cancer is substantial and growing, with burden differing by SDI. These results provide comprehensive and comparable estimates that can potentially inform efforts toward equitable cancer control around the world.
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