Effect of experimental toxic anemia on the pancreas

The decrease in hydrolytic capacity relative to polysaccharides observed in the initial hydrolysis phase of carbohydrates was expressed in the small intestinal secretion of α-amylase in the pancreas, a decrease in enzyme activity in the small intestinal chymus. Chronic exposure to toxicants leads to an increase in pancreatic tissue and enzyme activity in the blood due to a decrease in α-amylase activity in the small intestine. Decreased pancreatic secretion and increased secretion are indicative of pancreatic insufficiency. It was shown the regulator treatment of growing rats by hemotoxicants (phenilhydrasine and lead acetate) resulted to increase of incretion and decrease of secretion of pancreas. These changes take place at the histological destroy of pancreas. These data are shown the toxic anemia stimulates the development of pancreatitis in growing rats.

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