Features of the clinical course in lesions of the nose and paranasal sinuses in patients with postcovid syndrome.

Summary: The management of COVID-19 in the early stages and in the post-COVID period is so different and has not yet found its final answer for all patients from mild, moderate to severe forms of the disease.\n\n\nThe purpose of the study is to determine the clinical manifestations of lesions of the nose and paranasal sinuses in patients who have undergone COVID-19.\n\n\nMaterial and research methods. We examined 72 patients with diseases of the paranasal sinuses and their complications, frolicking in the first 2 months after undergoing COVID-19. SNP lesions manifested as necrotizing rhinosinusitis (NRS) with destruction of soft tissues and bone structures of the paranasal sinuses in all patients.\n\n\nResearch results. In the main group of 72 patients (100%), mild course of COVID-19 was observed in 9 (12.5%) patients, moderate course – in 23 (31.9%) patients, severe course – in 40 (55.6%) patients, while the percentage of lung tissue damage ranged from 12-60% at 95% CI: 10.1; 49.8%. HRS was accompanied by moderate edema of the periorbital region in 62 patients (86.1%), conjunctival injection was observed in all patients. All patients had a putrid odor. Nasal endoscopy revealed crusts and necrotic areas. Histological examination revealed fungal spores in 68 patients (94.4%). The ShiK reaction showed a positive result in 52 patients (72.2%). All patients had hyperglycemia more than 7 mmol /l.\n\n\nConclusions. The presence of anesthetized tissues in the nasal cavity may be the first diagnostic criterion for necrotizing rhinosinusitis. The presence of an immunodeficiency state (post-covid syndrome) is the basis for the development of necrotic rhinosinusitis.

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