THE EFFECTIVENESS OF PHOTODYNAMIC THERAPY IN THE CORRECTION OF CYTOKINE STATUS IN PATIENTS WITH CHRONIC SUPPURATIVE
Khamdamov B.ZHead of the Department of Faculty and Hospital Surgery, Urology of Bukhara State Medical Institute, DS. prof.Bukhara, UzbekistanU.I. NurovHead of the Department of Otorhinolaryngology and Ophthalmology of Bukhara State Medical Institute DS., associate professor; Bukhara, UzbekistanUktamov I. G.Basic doctoral student of the Bukhara State Medical Institute in the specialty of otorhinolaryngology; Bukhara, Uzbekistan
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Abstract: The effectiveness of standard and combined treatment using photodynamic therapy was evaluated based on the study of the levels of interleukin-2, interleukin-6 and tumor necrosis factor in 84 patients with chronic purulent otitis media. Photodynamic therapy was administered with aqueous solution of methylene blue every other day for 6 days (3 manipulation. It was found that by the end of the course of traditional therapy, a cytokine imbalance persists, indicating ongoing inflammatory changes. The inclusion of photodynamic therapy in the treatment regimen of patients with chronic suppurative otitis  media significantly improved cytokine status.
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