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CHARACTERISTICS OF COMORBIDE RHEUMATOID ARTHRITIS AND HYPOTHYREOSIS

Shodikulova Gulandom ZikriyaevnaAssociate Professor, Doctor of Medical Sciences, Department of Internal Medicine No. 3 Samarkand State Medical InstituteShonazarova Nodira KhudoiberdievnaAssistant of the Department of Internal Medicine №3 Samarkand State Medical InstituteHaydarova Gulchiroy ShodikulovnaStudent of group 306 of the medical faculty Samarkand State Medical Institute
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Аннотация

Clinicians are aware of frequent manifestations of endocrine gland function pathology in RA patients in the form of goiter, hypothyroidism, chronic adrenal insufficiency, etc. Thyroid hormones increase the activity of metabolic processes, stimulate lipogenesis, enhance the absorption of glucose by fat and muscle tissue, activate gluconeogenesis and glycogenolysis. Thyroid hormones (triiod-tyronine — T3, thyroxine — T4) enhance both resorption and synthesis of bone tissue, the production of glycosaminoglycans and proteoglycans in connective tissue.

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