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CONSEQUENCES OF CHRONIC HEART FAILURE IN THE DIAGNOSIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Ismailov Jamshid AbduraimovichPhD, Head of the Department of Internal Medicine №4, Samarkand State Medical University, Samarkand, UzbekistanAgababyan Irina RubenovnaPhD, Associate Professor Head of the Department of Therapy, Cardiology and Functional DiagnosticsTuraev Hikmatilla Negmatovichassistant of the Department of Clinical Pharmacology, Samarkand State Medical University Samarkand, UzbekistanAxatova Vazira Pardakulovnaassistant of the Department of Internal Medicine №4, Samarkand State Medical University Samarkand, UzbekistanNorchayev Mirjalolassistant of the Department of Internal Medicine №4, Samarkand State Medical University Samarkand, Uzbekistan
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Аннотация

Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease in patients with bronchial obstructive disease that has significant manifestations in the lungs and beyond. It is characterized by constant restriction of an air stream. Usually, the clinical course of the disease increases and depends on the pathogenic action of toxic particles or gases that cause chronic inflammation in the lungs. Identification of pathogenetic mechanisms that cause the occurrence of complications, and their treatment is one of the urgent problems of our time. Chronic obstructive pulmonary disease in patients with obesity, complicated by chronic heart failure, is characterized by the predominance of pathogenetic mechanisms of endothelial dysfunction, depending on the stage of COPD and the stage of CHF. The more severe COPD, the higher the levels of pro-inflammatory cytokines, which indicate the severity of endothelial dysfunction.

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