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PATHOGENETIC ASPECTS OF COVID-19

И.А. ИмамоваDepartment of infectious diseases and children infectious diseases, Candidate of Medical Sciences, Tashkent Medical Academy, Tashkent, UzbekistanMavlyuda Turabjanovna KarimovaDepartment of infectious diseases and children infectious diseases, Candidate of Medical Sciences, Tashkent Medical Academy, Tashkent, UzbekistanMaqsuda Turabjanovna ZubaydullayevaDepartment of infectious diseases and children infectious diseases, Candidate of Medical Sciences, Tashkent Medical Academy, Tashkent, UzbekistanTojigul Axmedovna NiyazovaDepartment of infectious diseases and children infectious diseases, Candidate of Medical Sciences, Tashkent Medical Academy, Tashkent, UzbekistanHamidulla Bashirovich MagzumovDepartment of infectious diseases and children infectious diseases, Candidate of Medical Sciences, Tashkent Medical Academy, Tashkent, UzbekistanIskandar Sergeyevich ShodmonovDepartment of infectious diseases and children infectious diseases, Tashkent Medical Academy, Tashkent, Uzbekistan [email protected]
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Аннотация

<strong>Abstract:</strong> to study in detail the pathogenetic aspects of COVID-19, which will allow us to understand the genesis of the development of the disease, as well as their complications. This will improve the medical care provided to this category of patients. The relationship between triggering the release of pro-inflammatory cytokines with the development of infiltration in endothelial cells, microvascular dysfunction, and an increase in respiratory failure is presented. Based on the literature review data, the article describes the genesis of the trigger development of respiratory pathology, as well as multiple organ failure, which contribute to the progression of COVID-19.

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