Justification of The Need to Determine the Level Of 25(OH) D 3 In the Blood Serum of Children to Assess the Quality of Rickitis Prevention

It has been established that the formation of rickets is promoted by a low level of the main metabolite of vitamin D, calcium and phosphorus in the blood serum. This was evidenced by the study of the biochemical parameters of the main indicators of calcium-phosphorus metabolism and the content of 25(OH) D 3 in the examined children before vitamin D prophylaxis when compared with the data of healthy children. Treatment with vitamin D 3 , along with restorative therapy, has significantly increased the effectiveness of preventing rickets. At the same time, there was a decrease in alkaline phosphatase, an increase in the content of 25(OH) D 3 in the blood serum, as well as in the level of calcium and phosphorus.

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