Modern Understanding OF the Pathogenesis OF Chronic Obstructive Pulmonary Disease in Comorbidity

Chronic obstructive pulmonary disease (COPD) is an urgent problem of modern medicine, which is primarily due to the high prevalence and large economic losses for the state [20]. COPD continues to hold the fourth place among the causes of death of the adult population [17], and the incidence rates are increasing annually. Intrahospital mortality in the exacerbation of the severe form of this disease reaches 29% [3]. COPD is a disease with a comorbid component. COPD polymorbidity includes cardiovascular pathology, diabetes mellitus (DM), depression, lung cancer, osteoporosis, etc. [7].

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