The significance of genetic mutations in the pathogenesis of the development of nephropathy in chronic kidney diseases of different etiologies

In modern medicine, a number of scientific studies are being conducted on the importance of genetic predisposition in the development of chronic kidney disease (CKD). This article presents the results of a study conducted to determine the level of APOL1 gene polymorphism in the pathogenesis of nephropathies of various etiologies in the Uzbek population. The analysis showed that the APOL1 gene polymorphism G1 and G2 mutations were found among the patients included in the study.

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