Computer Simulation Studies of Non-Thermal Plasma in Cancer Treatment
Аннотация
Non-thermal plasma (NTP), the fourth state of matter, holds promise in altering biological matter, particularly in cancer treatment. NTP influences cell signaling by modifying key components, such as membranes, proteins, and DNA. It selectively targets cancer cells through the generation of reactive oxygen and nitrogen species (RONS), which modify amino acids within proteins. Understanding these molecular mechanisms is vital for optimizing NTP's potential in oncology. This book chapter reviews recent computer simulations and experimental findings exploring NTP's impact on proteins in cancer therapy, providing insights into how protein modifications affect cancer cell behavior and therapy responses. This knowledge advances NTP-based cancer treatments, offering the potential for personalized and targeted therapies in the future.