The Association Between Vitamin D Status With Inflammatory Markers and Clinical Features in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease

This cross-sectional study assessed the association of vitamin D status with inflammatory markers and clinical features in 122 patients with metabolic dysfunction-associated steatotic liver disease (MASLD) who attended the polyclinics in Tabriz, Iran. The diagnosis of MASLD among participants was ultrasonography. The mean serum levels of interleukin-6 (P = .028), tumor necrosis factor-α ( P = .036), and alanine aminotransferase (ALT) ( P = .005) were significantly higher in the patients with vitamin D insufficiency than those with vitamin D sufficiency. Vitamin D insufficiency in patients with MASLD was found to be related to higher inflammation and severity of liver steatosis.

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