The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
Oysоra TоjikulovaSamarkand State University named after Sharof Rashidov, Samarkand, UzbekistanMuzaffar I. AsrarovResearch Institute of Biophysics and Biochemistry under the National University of Uzbekistan, Tashkent, UzbekistanBazarov BaxritdinSamarkand State University named after Sharof Rashidov, Samarkand, UzbekistanN R RakhmatovaSamarkand State University named after Sharof Rashidov, Samarkand, UzbekistanShokir TuramkulovSamarkand State University named after Sharof Rashidov, Samarkand, UzbekistanShoxsanam BaratovaKarshi State University, Karshi, Uzbekistan
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Аннотация
This article describes the results of a study conducted on rats on the effects of heavy metal salts, including Cd 2+ ions, on mitochondrial membranes. The experiments showed that heavy metals are one of the most dangerous sources of environmental pollution, and that they have a strong genotoxic, tumor-causing and cytotoxic effect when ingested. Cd 2+ poisoning occurs in the metallurgical industry through inhalation of atmospheric air, consumption of contaminated food and water, and cigarette smoke. The studies showed that the studied heavy metal salts, Cd 2+ ions, negatively affect the structure of the mitochondrial membrane, increasing the passive permeability of the membrane for monovalent H + , K + and Na + cations.
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