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Association of serum levels of 25-hydroxyvitamin D with dental status, socio-demographic characteristics and subjective complaints in the adult population of Tashkent city

S. P. RubnikovichBelarusian State Medical UniversityO.E. BekjanovaTashkent State Dental InstituteJ. J. MannanovTashkent State Dental Institute
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Аннотация

Vitamin D deficiency is recognized as a global pandemic. The identification of the relationship between hypovitaminosis D, dental pathology, gender and age, and social status, and subjective health complaints may be necessary for a preliminary diagnosis of hypovitaminosis D. Given the limited body of research and the importance of therapy, the main purpose of this research was to develop a method for detecting hypovitaminosis D during dental appointments based on a comprehensive assessment of the dental, gender and age, social status, patient complaints, as well as an evaluation of the diagnostic information these factors provide. The diagnostic significance and informative value of dental status, somatic characteristics, and patient complaints in the diagnosis of hypovitaminosis D have been established. When one of the predictors of hypovitaminosis D is present, the probability of detection ranges from 51.70 to 89.00 %. The detection of two or more high-intensity dental pathologies in a single patient increases this probability to 77.89–92.00 %. The combination of dental pathology with demographic characteristics increases the risk of hypovitaminosis D to 88.69‒93.00 %. The concurrent presence of characteristic complaints increases this risk to 95.00 %. A probabilistic model has been developed to evaluate the sensitivity and specificity of diagnostic tests for the presence of vitamin D deficiency without reference to laboratory research methods. A high degree of informative value of combined screening with the calculation of the risk of vitamin D deficiency has been proven

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