Gene Editing Technologies as a Tool for Preventing Unwanted Modifications in Human Cell Structures
Аннотация
Genetic alterations and other undesirable changes in human cells contribute to various health issues, such as genetic disorders, cancer, and degenerative illnesses. The rise of gene editing technologies has opened up new possibilities to not only grasp the mechanisms of these conditions but also to prevent or rectify them at their genetic origin. This research paper examines the development of gene editing technologies, starting with initial methods like zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) and progressing to contemporary techniques such as CRISPR-Cas9, base editing, and prime editing.The article employs a literature review approach, integrating scholarly articles, books, and reports to examine how these technologies operate, their comparative advantages and drawbacks, and their possible uses in human health. The results emphasize the revolutionary effectiveness of CRISPR-Cas9, the accuracy of base and prime editing for point mutations, and the essential contribution of TALENs and ZFNs in establishing modern techniques. Summarizing research, ethical supervision, and technological improvements had suggested that these tools could revolutionize precision medicine and greatly lessen the impact of genetic disorders.
Перевод пока недоступен