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Attention-enhanced bidirectional LSTM for multivariate ECG arrhythmia classification: a deep learning approach with clinical validation

Nadira TashtemirovaScientific Secretariat, Research Institute, Research Institute for the Development of Artificial Intelligence, Tashkent, Uzbekistan
ABI

Аннотация

Cardiovascular diseases (CVDs) are the top cause of death in the world, responsible for some 32% of all deaths. Despite the fact that electrocardiogram (ECG) is still the most commonly used non-invasive diagnostic tool for cardiac arrhythmia detection, automated classification of complex multivariate ECG signals remains a persistent challenge due to wave non-stationarity, inter-patient variability and severe class imbalance. We introduce a novel deep learning framework, called ATT-BiLSTM, for real-time ECG arrhythmia classification, combining bidirectional long short-term memory (BiLSTM) networks with a multi-head self-attention mechanism. The architecture consists of two BiLSTM encoder layers with residual connections, followed by a scaled dot-product attention module with eight heads, dynamically applied to P-wave, QRS complex and T-wave morphology features. The model was tested on the MIT-BIH Arrhythmia Database and the PTB-XL large-scale ECG database, achieving 96.4% classification accuracy, macro-averaged F1 score of 95.8% and AUC-ROC of 0.982. Comparative experiments with CNN-LSTM hybrid networks, Temporal Convolutional Networks (TCN), vanilla Transformer encoder, and standard BiLSTM further demonstrate the superiority of ATT-BiLSTM. Ablation studies confirm that multi-head self-attention contributes the greatest performance gain (+1.4% accuracy), with all improvements statistically significant (p < 0.01) via paired Wilcoxon signed-rank tests. This work advances scalable, AI-driven cardiovascular care by delivering clinical-grade diagnostic accuracy with real-time inference for automated cardiac monitoring.

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