Assessment OF Renal Functional Status in Obese Pregnant Women in the Development OF Preeclampsia

Obesity in pregnancy has become a significant public health concern due to its strong association with maternal and fetal complications, particularly preeclampsia. Preeclampsia is a multisystem disorder characterized by hypertension and renal dysfunction, which can adversely affect both maternal and fetal outcomes. The present study aimed to assess the functional status of the kidneys in obese pregnant women and evaluate its role in the development of preeclampsia. Biochemical markers, including serum creatinine, blood urea nitrogen (BUN), proteinuria, and microalbuminuria, were measured. Hemodynamic assessment was performed using Doppler ultrasonography to evaluate renal artery resistance and perfusion. The study demonstrated that obese pregnant women exhibit significant alterations in renal function, including decreased estimated glomerular filtration rate (eGFR) and elevated proteinuria, which were strongly associated with preeclampsia development. Early identification of renal dysfunction in this high-risk group allows timely interventions, risk stratification, and improved maternal and fetal outcomes. These findings highlight the importance of integrating renal functional assessment into routine prenatal care for obese women.

Перевод пока недоступен