Dihydromyricetin: an emerging compound with comprehensive effects on multiple systems
Chengyi HeCollege of Integrative Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, ChinaYunfei ChenDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaJiao XieHealth Management Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaMiao LuoDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDavid FisherDepartment of Medical Biosciences, Faculty of Natural Sciences, University of The Western Cape, Cape Town, South AfricaNguyễn Thị Thu HiềnHai Phong University of Medicine and Pharmacy, Haiphong, VietnamErkin MusabaevThe Research Institute of Virology, Ministry of Health, Tashkent, UzbekistanYiping DangDepartment of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaLei ZhaoDepartment of Infectious Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaXia YinDepartment of Vascular Surgery, The Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China
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Аннотация
Dihydromyricetin (DHM or DMY) is a flavonoid derived from natural sources with a range of confirmed biological benefits. It exhibits anti-inflammatory, antioxidant, anti-tumor, and anti-viral activities. DHM is recognized for its high biosafety, making it a promising subject for further research. This article offers a comprehensive overview of DHM's pharmacological properties, mechanisms, and recent research developments in the cardiovascular, urinary, digestive, nervous, and respiratory systems. The review summarizes DHM's biological effects and associated signaling pathways, providing novel insights for its clinical application.
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