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STUDY OF THE INFLUENCE OF A TETRAHYDROISOQUINOLINE BROMINE DERIVATIVEON FREE RADICAL OXIDATIVE PROCESSES

Umarova M.RS.Y. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Mirzo Ulugbek Str. 77, 100170, Tashkent, UzbekistanTerenteva E.OS.Y. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Mirzo Ulugbek Str. 77, 100170, Tashkent, UzbekistanAzimovaSh.SS.Y. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Mirzo Ulugbek Str. 77, 100170, Tashkent, Uzbekistan
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Аннотация

The development of novel antileukemic agents requires not only high cytotoxic efficacy but also a clear understanding of their underlying mechanisms of action. Oxidative stress–mediated pathways are frequently implicated in cancer cell death; however, alternative mechanisms may offer therapeutic advantages [1].

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