Characteristics of Clinical Manifestations in Children with Type 1 Diabetes Mellitus After Covid-19 Infection

The purpose of the study: To study the characteristics of clinical indicators in children with type 1 diabetes mellitus after COVID-19 infection. We conducted a study of 254 children with type 1 diabetes who had COVID-19 infection and were treated at the pediatric department of the Republican Specialized Scientific and Practical Medical Center of Endocrinology named after Academician E.H. Turakulov and 30 practically healthy children of the same age and gender. Children with type 1 diabetes mellitus who have experienced COVID-19 infection demonstrate a higher frequency of cardiovascular, autonomic, and neurological manifestations, along with an increased prevalence of chronic diabetic complications, particularly in older age groups. These alterations are likely associated with post-infectious inflammatory responses, endothelial dysfunction, and metabolic disturbances contributing to the progression of microvascular and neurocardiac impairments. These findings indicate that COVID-19 may act as an aggravating factor in the development and progression of chronic complications in pediatric patients with type 1 diabetes mellitus and highlight the importance of early diagnosis, regular cardiological evaluation, and comprehensive multidisciplinary follow-up in the post-COVID period.

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