COMPARATIVE ANALYSIS OF THE EFFECTIVENESS OF COMPLEX TREATMENT OF GLAUCOMATIC OPTIC NEUROPATHY AND TRAUMATIC OPTIC NEUROPATHY

Resume. Relevance. The main significance of vision loss and optic nerve atrophy In traumatic optic neuropathy (TON) and glaucomatous optic neuropathy (GON), the cause is attributed to vascular changes in the blood supply to the optic nerve and retina. Purpose of the study. To determine the effectiveness of complex neuroprotective treatment of patients with GON and TON based on functional and hemodynamic parameters. Material and methods. We examined 22 patients (33 eyes) diagnosed with primary open-angle glaucoma ( POAG) with compensated intraocular pressure (IOP) and 20 patients (20 eyes) previously operated on for various midface bone fractures (MFBF) complicated by TON. Complex treatment included: Ethyl methylhydroxypyridinesuccinate 50 mg ( Mexidol dissolved in 100 ml of 0.9% sodium chloride solution) intravenously by drip for 10 days, Lyophilisate 10 mg - 2.0 ml ( Cortexin dissolved in 0.5 ml of 0.5% Novocaine solution) in a dose of 0.5 ml, which was administered parabulbarly for 10 days . Results and conclusion. The proposed regimen of drug prevention of TON and GON leads to persistent preservation of visual functions and improvement of hemodynamic parameters (83%). Key words: glaucomatous optic neuropathy, traumatic optic neuropathy, neuroprotection, Mexidol, microcirculation

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