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Ancient DNA from the First European Farmers in 7500-Year-Old Neolithic Sites

Wolfgang HaakEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaPeter ForsterEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaBarbara BramantiEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaShuichi MatsumuraEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaGuido BrandtEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaMarc TänzerEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaRichard VillemsEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaColin RenfrewEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaDetlef GronenbornEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaKurt W. AltEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, EstoniaJoachim BürgerEstonian Biocentre, Tartu University, 23 Riia Str, Tartu, 51010, Estonia
2005en
ABI

Аннотация

The ancestry of modern Europeans is a subject of debate among geneticists, archaeologists, and anthropologists. A crucial question is the extent to which Europeans are descended from the first European farmers in the Neolithic Age 7500 years ago or from Paleolithic hunter-gatherers who were present in Europe since 40,000 years ago. Here we present an analysis of ancient DNA from early European farmers. We successfully extracted and sequenced intact stretches of maternally inherited mitochondrial DNA (mtDNA) from 24 out of 57 Neolithic skeletons from various locations in Germany, Austria, and Hungary. We found that 25% of the Neolithic farmers had one characteristic mtDNA type and that this type formerly was widespread among Neolithic farmers in Central Europe. Europeans today have a 150-times lower frequency (0.2%) of this mtDNA type, revealing that these first Neolithic farmers did not have a strong genetic influence on modern European female lineages. Our finding lends weight to a proposed Paleolithic ancestry for modern Europeans.

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